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Food safety is one of the concerns and objectives of the current policy of several developing and developed countries. It aims to improve the life quality (increasing quality and years of healthy life, and eliminating health disparities) of their citizens and is considered to be one of the challenging goals for the twenty- rst century (COM 2000; USDHHS 2000; WHO 2004; PAHO 2008). Food safety has increasingly become a current issue, owing to changing consumer eating habits, changing products and production practices, changing population (aging of the population and the increased number of immunocompromized individuals), and increased food infections. In fact, the global incidence of food-borne diseases is dif cult to estimate, but it has been reported that in 2005 alone, 1.8 million people died from diarrhoeal diseases (WHO 2007). The priority is to reduce food-borne diseases. In addition, in a global market, food safety is a priority for food trade and is an economic issue. Food trade growth and food marketing changes lead to exposure to new risks and greater potential consequences of food-borne illness outbreaks. Consumers in industrialized countries have become more aware of the potential food safety hazards through media reports and increased availability of scienti c knowledge. The challenge is to develop integrated effective food safety systems, essential to maintain consumer con-

Sensory input to the LGI system is gathered from the environment via the displacement of approximately 1000 cuticular hairs (termed sensory afferents) covering the abdomen of the animal These hairs operate in manner broadly similar to the spider trichobothria that were considered as a case study earlier in this chapter Their mechanism is more similar to that of the insects than to that of the spider however, in that a bipolar cell that is sensitive to direction of movement serves each hair The bipolar cells communicate with the LGI either directly or via a bank of 25 50 sensory interneurons Each abdominal segment contains a single LGI, and these connect to one another to provide a chain for the transmission of signals from the tail all of the way up the animal s dorsal nerve cord.

debate between psychologists and the legal community that continued intermittently for the rest of the century He asserted that the lawyer alone is obdurate in failing to recognize the importance of applied psychology M nsterberg s assertions were so arrogant that they provoked a scathing response from legal scholar John Wigmore (1909), who created transcripts of a mythical libel trial in which Professor M nsterberg was sued for libel by the legal eld for his assertions and was found guilty of claiming more than he could offer The plaintiffs lawyer, Mr Tyro, criticized the lack of relevant research publications available (none had yet been published in English when M nsterberg s book was published), and noted that eminent European psychologists such as Sigmund Freud and Wilhelm Stern had cautioned against overzealous application of psychological ndings.

Output from the LGI ultimately causes the rapid contraction of the abdominal fast exor muscles, exing the abdomen as shown in Fig 211 Two routes achieve this The rst is via direct excitation of motor giants (MoGs) These neurons form a direct contact between the LGI and all of the fast exor muscle bers in each abdominal segment The second route interposes an interneuron called a segmental giant (SG) between the LGI and a set of fast exor neurons (FFs), each of which connects to a few of the fast exor muscle bers within a segment Figure 212 shows the arrangement of the various components of the LGI-mediated tail- ip system both in the tail of a cray sh and as a simpli ed circuit diagram to explain its connectivities.

It should be obvious from the circuit diagram that the LGI has a special and central role in the system Physically it represents a convergence of inputs from a large number of sensory cells and it has an effect upon a wide range of motor cells This crucial position within the system identi ed the LGI as a key candidate to be the command neuron or on/off switch of the tail- ip response But being in the right place both physically and in the signal sequence does not actually prove that the LGI is the command neuron In order to do this we need to consider three further lines of evidence Firstly, the LGIs can be described as being both suf cient and necessary for the tail- ipping to take place Simple direct electrical stimulation of a giant interneuron will result in.